Computational modeling of AGO-mediated molecular inhibition of ARF6 by miR-145
نویسندگان
چکیده
منابع مشابه
Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): inhibition of bladder cancer cell aggressiveness
In microRNA (miRNA) biogenesis, the guide-strand of miRNA integrates into the RNA induced silencing complex (RISC), whereas the passenger-strand is inactivated through degradation. Analysis of our miRNA expression signature of bladder cancer (BC) by deep-sequencing revealed that microRNA (miR)-145-5p (guide-strand) and miR-145-3p (passenger-strand) were significantly downregulated in BC tissues...
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ژورنال
عنوان ژورنال: Indonesian Journal of Biotechnology
سال: 2020
ISSN: 2089-2241,0853-8654
DOI: 10.22146/ijbiotech.55631